AI/ML-enabled growing of small molecules inside protein cavities

Parc Científic de Barcelona i Chemotargets

How to anticipate and address early both pre-clinical toxicity and post-marketing safety

Parc Científic de Barcelona  -    Sala Dolors Aleu

In this presentation, organised by <a href="https://chemotargets.com/" title="https://chemotargets.com/" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Chemotargets </a>and <a href="https://https://www.pcb.ub.edu/" title="https://https://www.pcb.ub.edu/" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Parc Científic de Barcelona</a>, the attendees will be offered a hands-on session on how to anticipate and address early both pre-clinical toxicity and post-marketing safety and, in a complete change of paradigm from virtual screening to smart generation, will learn about our new concept on AI-/ML-enabled growing of small molecules from fragment seeds within protein cavities of difficult-to-treat targets.Chemotargets is a Barcelona-based biotechnology company founded in 2006 by Dr. Jordi Mestres. Its mission has always been to accelerate and optimise the process of creating new medicines, reducing the time, costs and risks associated with traditional pharmaceutical development. In 2017, the company developed CLARITY®, a computational platform to predict the off-target pharmacology of small molecules as a means to anticipate potential mechanistic adverse reactions. The product was quickly adopted by pharmaceutical companies worldwide and the FDA. In 2022, CLARITY® was licensed exclusively to Chemical Abstracts Service to become the technology foundation of CAS BioFinder, the new discovery intelligence platform by CAS.In the past two years, Chemotargets has evolved from a company focused on software development to a biotechnology company with its own drug discovery projects, especially in the field of oncology and rare diseases. In addition, it maintains a network of international collaborations with academic institutions, pharmaceutical companies and regulatory bodies, consolidating its position as a global reference in the application of artificial intelligence to the development of new medical treatments. Agenda09.30 - 09.45 Introducció by Grisha Domakowski, PCB’s Commercialization and Communication Director09.45 - 10.15 - Jordi Mestres, Chemotargets Founder &amp; CEO10.15 - 10.45 - Elisabet Gregori, Product Manager, Chemotargets10.45 - 11.15 - Xavier Jalencas, Generative Drug Discovery Unit, Chemotargets11.15 - 11.20 - Q&amp;A11.20 - 11.45 - Coffee networking About the speakersThe session will be introduced by Jordi Mestres, founder and CEO of Chemotargets. Jordi has over 30 years of experience and expertise in all aspects of computational drug discovery, from software development to project management. He is the recipient of the prestigious Hansch Award from the QSAR, Chemoinformatics and Modelling Society (2006) and a Fellow of the Royal Society of Chemistry (2018).Elisabet Gregori, PhD, is a Product Manager and Computational Biologist with over 15 years of experience bridging drug discovery and data science. She was formerly a Lab Head at Novartis, where she led computational chemistry initiatives in phenotypic-based drug discovery, and currently oversees the development of predictive safety modeling platforms at Chemotargets. She holds a PhD in Life and Health Sciences from UPF and did her postdoctoral research at UCSF.Xavier Jalencas received a BSc in Biology from Pompeu Fabra University in 2005. He completed his PhD in Biomedicine at the same university in 2013 within the Systems Pharmacology Group under the supervision of Dr. Jordi Mestres. After a postdoctoral stay in the group, he joined Chemotargets in 2019, where he currently leads the Generative Drug Discovery Unit, applying AI-driven methods to address challenging drug targets.

Our {communityGuidelinesLink} describe the sort of content we prohibit on Eventbrite. If you suspect an event may be in violation, you can report it to us so we can investigate.

To report other categories of prohibited or illegal content, submit {link}

AI/ML-enabled growing of small molecules inside protein cavities

More events from Parc Científic de Barcelona i Chemotargets

Discover more events from Parc Científic de Barcelona i Chemotargets, from Science & Tech to other experiences you might love.

Still looking for the right event?

Explore all events in Barcelona and filter by date, category, and more to find the perfect fit.

AI/ML-enabled growing of small molecules inside protein cavities

More events from Parc Científic de Barcelona i Chemotargets

Discover more events from Parc Científic de Barcelona i Chemotargets, from Science & Tech to other experiences you might love.

More Science & Tech events

Browse more Science & Tech events with different dates, prices, and formats to find your next great experience.

Still looking for the right event?

Explore all events in Barcelona and filter by date, category, and more to find the perfect fit.